DNA paternity tests: how they work and how to do one
A DNA paternity test works a lot like other genetic tests, such as to discover distant relatives, ancestral origins, or …
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DNA alkylation drug may improve outcomes for adolescents and young adults with central nervous system tumors
In a phase II clinical trial, the drug 4-demethyl-4-cholesteryloxycarbonylpenclomedine (DM-CHOC-PEN) improved survival for some adolescent and young adult (AYA) patients …
Damaging DNA builds up in the eyes to drive blinding age-related macular degeneration
Damaging DNA builds up in the eyes of patients with geographic atrophy, an untreatable, poorly understood form of age-related macular …
Structure of BRCA2 protein complex critical for DNA repair solved
The initials BRCA2 may be best known for a gene associated with many cases of breast cancer, and the protein …
Study identifies DNA signatures linked to heart disease
A new study identifies DNA signatures associated with risk for cardiovascular disease, a discovery that could lead to opportunities for …
DNA tags enable blood-based tests to assess cancer treatment outcomes
Cell-free DNA (cfDNA) shed into the blood was discovered in the late 1940s but with rapid advances in genomics and …
DNA methylation changes in neurons of bipolar disorder patients
A research collaboration based in Kumamoto University, Japan, has revealed the DNA methylation status of gene transcriptional regulatory regions in …
Humoral immunity developed by DNA vaccine INO-4800 is effective against SARS-CoV-2 variants
A team of international scientists recently demonstrated that antibodies generated in response to the DNA vaccine INO-4800 can effectively neutralize …
New method for scDNA sequencing provides insights into breast cancer evolution
Overcoming previous technical challenges with single-cell DNA (scDNA) sequencing, a group led by researchers at The University of Texas MD …
What are Deacetylase Inhibitors?
Histone deacetylases are enzymes involved in the modification of histones in order to allow DNA to wrap around them tightly. …
Telomere Shortening, Aging, and Cancer
Skip to: What are Telomeres? Function of Telomeres Telomere Shortening and Aging Telomerase and Stem Cells Telomere Lengthening in Cancer …
Why Cryo-EM is Gaining Popularity in Structural Biology
By Shelley Farrar, MSc, BSc Cryo-electron microscopy, also known as Cryo-EM, is a technique for visualizing macromolecular structures which has …
What is Time-Resolved Fluorescence Spectroscopy?
Time-resolved fluorescence spectroscopy is a spectroscopy technique used to monitor interactions between molecules and motions that occur in the short …
How to Store DNA
DNA is very sensitive and can easily degrade in certain conditions. Thus, proper storage is required to ensure high experimental …
Risk of deadly skin cancer may be gauged by accumulated DNA damage
Risk for melanoma, the most deadly skin cancer, can be estimated long before detection of any suspicious moles, according to …
Coronavirus may dice heart muscle fibers into tiny snippets, remove cells’ DNA
The new coronavirus seems to slice heart muscle fibers into small, precisely sized fragments — at least when it infects …
DNA may hold the key to protecting populations from COVID-19
Scientists from The University of Western Australia’s Faculty of Science are part of a global team that is developing a …
Using machine learning to detect lung cancer DNA in blood
A large team of researchers affiliated with multiple institutions across the U.S. has found that it might be possible to …