Mapping the mouse brain, and by extension, the human brain too
The circuits of the human brain contain more than 100 billion neurons, each linked to many other neurons via thousands …
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New mouse model unlocks drug testing of hormone-sensitive human breast cancer
Scientists at the Medical College of Wisconsin Cancer Center and an international team of collaborators have generated mice with an improved hormone …
‘Humanized’ mouse model selects better match for organ transplant
A “humanized” mouse model equipped with the immune system of a patient who needs an organ transplant beats current measures …
GluN3A knockout mouse: Alternative model for Alzheimer’s neurodegeneration
In recent debate over the FDA’s approval of the Alzheimer’s drug aducanumab, we’ve heard a lot about the “amyloid hypothesis.” …
Gene therapy strategy found effective in mouse model of hereditary disease TSC
Patients with tuberous sclerosis complex, a genetic disorder characterized by the growth of noncancerous tumors in multiple organs of the …
A library of mouse genes to look up the best liver cancer treatment
If you want to get smarter, the library is a good place to start. And for cancer researchers, smarter treatment …
Diabetes drug metformin shows promise in mouse study for a common type of ALS
An FDA-approved diabetes drug shows early signs of promise against the most common genetic form of amyotrophic lateral sclerosis, a …
Mouse study shows how advancing glioma cells scramble brain function, blood flow
The first sign of trouble for a patient with a growing brain tumor is often a seizure. Such seizures have …
New ingredient in cocaine vaccine shows promise in mouse study
A new ingredient added to a current cocaine vaccine appears to enhance its effectiveness in blocking the drug’s “high” when …
A mouse model of prostate cancer bone metastasis in a syngeneic immunocompetent host
The Research Team reports the establishment of B6Ca P, an allograft tumor line from a Hi-Myc transgenic mouse that had …
Obese mouse mothers trigger heart problems in offspring
A diet high in fats and sugars is known for its unhealthy effects on the heart. Scientists now have found …
Meningitis changes immune cell makeup in the mouse brain lining
Meningitis, a group of serious diseases which infect the brain’s lining, leaves its mark and can affect the body’s ability …
New mouse model reminiscent of Leigh syndrome sheds light on mechanisms of neurodegeneration
Leuven researchers led by professor Bart De Strooper (VIB-KU Leuven) have identified a new role for PARL, a protein linked …