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The Role of Coenzyme Q10 in Our Body

Although we get a limited amount of coenzyme Q10 from dietary sources, the majority of CoQ10 in humans is manufactured by our own cells. The biosynthesis of coenzyme Q10 is a 17-step process that requires the following nutrients:riboflavin, niacinamide, pantothenic acid, pyridoxine, cobalamin(B12), folic acid, vitamin C, and numerous other trace elements. Consequently, there are many ways the complex synthesis of coenzyme Q10 can be interrupted. It is probable that many people with health problems are suffering from a coenzyme Q10 deficiency due to inadequate dietary intake of the necessary nutrients and/or ingestion of one or more drugs that interrupt the synthesis of coenzyme Q10.

Symptoms of coenzyme Q10 deficiency include congestive heart failure, high blood pressure, angina, mitral valve prolapse, stroke, cardiac arrhythmia, cardiomyopathy, lack of energy, gingivitis, and generalized weakening of the immune system. Since coenzyme Q10 is intimately involved in the production of energy, a deficiency of CoQ10 first affects the heart and cardiovascular system because the heart is the most energy demanding muscle in the human body. The results of some studies suggest that congestive heart failure is primarily a coenzyme Q10 deficiency disease.

Coenzyme Q10 (CoQ10) is one of the most important nutrients in the human body. It is a fat-soluble vitamin-like compound that is also known as ubiquinone from the word ubiquitous, which means “every where”. Coenzyme Q or ubiquinone compounds are synthesized in the cells of all living organisms including plants, animals and man. There are ten coenzyme Q compounds that occur throughout nature, but only coenzyme Q10 is synthesized in humans.

Coenzyme Q10 also helps to protect against the toxic side effects of other widely used drugs such as adriamycin, beta-blockers, and drugs used for psychiatric disorders. Coenzyme Q10 appears to be very safe. No studies have reported toxicity or adverse side effects. No RDA has been set for coenzyme Q10. Normal supplement dosage ranges from 30-100 mg. There have been some reports of treating health conditions (e.g. sever cardiovascular disease and advanced breast cancer) with dosages from 300-360 mg/day. Utilization of high dosage to treat severe health problems should only be done under the supervision of a physician.

Coenzyme Q compounds exist in the cells of all plants and animals. However, the level of coenzyme Q10 that we obtain from the diet is believed to be inadequate to meet the needs for optimal health and wellness.